290 Quality of Clinical Practice Guidelines for Laparoscopic Surgery: Systematic Review

Abstract Aim Guidelines on laparoscopic surgery are essential for providing guidance to achieve safe and effective treatments. In this systematic review, we investigated the true extent of grades recommendation which were supported by evidence in guidelines whether depended upon quality guidelines. Method We searched PUBMED EMBASE surgical published between 1st March 2016 2019.To determine evidence, determined disagreement grading guideline author independent evaluation. used AGREE-II Tool ‘rigour development’ ‘clarity presentation’ domains assess performed a mixed effects generalised linear regression modelling using binary distribution logit link GLIMMIX procedure Statistical Analysis System (SAS) software. Results analysed 1905 statements from 63 retrieved. The median scores development’, presentation’, ‘editorial independence’ 0.43, 0.72 0.63. interquartile ranges 0.094, 0.25 0.38. domain was only determinant authors Conclusions There is variation can be predict Guideline users should use before developing local clinical policies.